Our Biomedical Engineering research is interdisciplinary, using the skills and knowledge of academics from Engineering and Life Sciences. Research and development are being conducted in different areas including diagnostics, cardiovascular mechanics, organ-on-a-chip, prosthetics and diabetes. This has led to the development of smart devices for rapid screening, monitoring, diagnosis and therapy of diseases at the point of care and/or in laboratory settings.
Case 明星八卦: Assessing the Combined Effects of Preventable Factors on Breast Cancer
Lifestyle factors and environmental contaminants, including endocrine disrupting chemicals (EDCs), play a role in breast cancer development, but human studies linking EDCs to cancer are often inconclusive. This is mainly because EDCs are studied individually and in concentrations that don’t match our day to day exposure. This project, funded by Breast Cancer UK, examines the impact of mixtures of endocrine disrupting chemicals and saturated fats (that may result from a high fat diet) on the early stages of breast cancer, using an exciting new three-dimensional breast cancer model system known as “Breast-on-chip” (3Dcell culture). This method of culturing different types of breast cells more closely,mimics how breast cells behave in the body and provides a representative alternative to current laboratory and animal-based methods. The project aims to provide guidance for chemical regulation and a framework for further public information and practical advice on ways to reduce exposure to factors that contribute to breast cancer risk.
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