Scale-up
Most chromatography processes are difficult to scale up, but the liquid flow processes in the ABC, scale up remarkably well by just increasing the bore of the tubing. Of course as the tubing bores get bigger the centrifuges themselves get bigger, but the magnitude of the force field is always kept the same, from the Mini centrifuge (tubing bore 0.8mm) through to the Maxi centrifuge (tubing bore 10mm).
| Name | Specifications |
|---|
| Mini CCC |
- Scale of application: Analytical
- Processing rate: mg/hr
- Main rotor radius (mm): 50
- Volume of coils (ml): 17
- Coil bore (mm): 0.8
- Max rotor speed (rpm): 2100
- Typical flow range (ml/min): 0.1 - 2
- Typical run time (min): 30
|
|---|
| Spectrum CCC |
- Scale of application: Semi/Prep
- Processing rate: mg-g/hr
- Main rotor radius (mm): 85
- Volume of coils (ml): 143
- Coil bore (mm): 1.6
- Max rotor speed (rpm): 1600
- Typical flow range (ml/min): 0.5-10
- Typical run time (min): 30
|
|---|
| Midi CCC |
- Scale of application: Preparative
- Processing rate: g/hr
- Main rotor radius (mm): 110
- Volume of coils (ml): 912
- Coil bore (mm): 4.0
- Max rotor speed (rpm): 1400
- Typical flow range (ml/min): 10-100
- Typical run time (min): 30
|
|---|
| Maxi CCC |
- Scale of application: Pilot
- Processing rate: kgs/day
- Main rotor radius (mm): 300
- Volume of coils (ml): 4600
- Coil bore (mm): 10.0
- Max rotor speed (rpm): 850
- Typical flow range (ml/min): 100-1000
- Typical run time (min): 30
|
|---|